Model for the distributions of k-mers in DNA sequences

Yaw Hwang Chen, Su Long Nyeo, Chiung Yuh Yeh

研究成果: Article同行評審

8 引文 斯高帕斯(Scopus)

摘要

The evolutionary features based on the distributions of k-mers in the DNA sequences of various organisms are studied. The organisms are classified into three groups based on their evolutionary periods: (a) E. coli and T. pallidum (b) yeast, zebrafish, A. thaliana, and fruit fly, (c) mouse, chicken, and human. The distributions of 6-mers of these three groups are shown to be, respectively, (a) unimodal, (b) unimodal with peaks generally shifted to smaller frequencies of occurrence, (c) bimodal. To describe the bimodal feature of the k-mer distributions of group (c), a model based on the cytosine-guanine "CG" content of the DNA sequences is introduced and shown to provide reasonably good agreements.

原文English
文章編號011908
期刊Physical Review E - Statistical, Nonlinear, and Soft Matter Physics
72
發行號1
DOIs
出版狀態Published - 2005 七月

All Science Journal Classification (ASJC) codes

  • 統計與非線性物理學
  • 統計與概率
  • 凝聚態物理學

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