Molecular markers of cancer stem cells verified in vivo

Y. S. Kim, A. M. Kaidina, J. H. Chiang, K. N. Yarygin, A. Yu Lupatov

研究成果: Review article同行評審

16 引文 斯高帕斯(Scopus)


This systematic review aims to analyze molecular markers of cancer stem cells. Only studies that confirmed tumor-initiating capacity of this population by in vivo assay in immunodeficient mice were included. Final sample of papers that fully correspond with initial aim consists of 97 original studies. The results of their analysis reveal that markers commonly used for cancer stem cells deriving were as follows: CD133, CD44, ALDH, CD 34, CD24 and EpCAM. The review also contains description of molecular features of some cancer stem cell markers, modern approaches to cancer treatment by targeting this population and brief assessment of cancer stem cell theory development.

頁(從 - 到)228-238
期刊Biomeditsinskaya Khimiya
出版狀態Published - 2016

All Science Journal Classification (ASJC) codes

  • 生物化學、遺傳與分子生物學 (全部)


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