Molecular markers of cancer stem cells verified in vivo

Y. S. Kim; A. M. Kaidina; J. H. Chiang; K. N. Yarygin; A. Yu Lupatov

doi:10.18097/PBMC20166203228

Molecular markers of cancer stem cells verified in vivo

Y. S. Kim, A. M. Kaidina, J. H. Chiang, K. N. Yarygin, A. Yu Lupatov

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研究成果: Review article › 同行評審

16 引文斯高帕斯（Scopus）

摘要

This systematic review aims to analyze molecular markers of cancer stem cells. Only studies that confirmed tumor-initiating capacity of this population by in vivo assay in immunodeficient mice were included. Final sample of papers that fully correspond with initial aim consists of 97 original studies. The results of their analysis reveal that markers commonly used for cancer stem cells deriving were as follows: CD133, CD44, ALDH, CD 34, CD24 and EpCAM. The review also contains description of molecular features of some cancer stem cell markers, modern approaches to cancer treatment by targeting this population and brief assessment of cancer stem cell theory development.

原文	English
頁（從 - 到）	228-238
頁數	11
期刊	Biomeditsinskaya Khimiya
卷	62
發行號	3
DOIs	https://doi.org/10.18097/PBMC20166203228
出版狀態	Published - 2016

All Science Journal Classification (ASJC) codes

一般生物化學，遺傳學和分子生物學

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10.18097/PBMC20166203228

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AU - Chiang, J. H.

AU - Yarygin, K. N.

AU - Lupatov, A. Yu

PY - 2016

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N2 - This systematic review aims to analyze molecular markers of cancer stem cells. Only studies that confirmed tumor-initiating capacity of this population by in vivo assay in immunodeficient mice were included. Final sample of papers that fully correspond with initial aim consists of 97 original studies. The results of their analysis reveal that markers commonly used for cancer stem cells deriving were as follows: CD133, CD44, ALDH, CD 34, CD24 and EpCAM. The review also contains description of molecular features of some cancer stem cell markers, modern approaches to cancer treatment by targeting this population and brief assessment of cancer stem cell theory development.

AB - This systematic review aims to analyze molecular markers of cancer stem cells. Only studies that confirmed tumor-initiating capacity of this population by in vivo assay in immunodeficient mice were included. Final sample of papers that fully correspond with initial aim consists of 97 original studies. The results of their analysis reveal that markers commonly used for cancer stem cells deriving were as follows: CD133, CD44, ALDH, CD 34, CD24 and EpCAM. The review also contains description of molecular features of some cancer stem cell markers, modern approaches to cancer treatment by targeting this population and brief assessment of cancer stem cell theory development.

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JO - Biomeditsinskaya Khimiya

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Molecular markers of cancer stem cells verified in vivo

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