Multi-Modal, Implantable Colon Activity Sensor

Steve J.A. Majerus, Dario Cabal, Yaneev Hacohen, Brett Hanzlicek, Aref Smiley, Yushan Wang, Wentai Liu, Muriel Larauche, Mulugeta Million, Margot S. Damaser, Dennis Bourbeau

研究成果: Conference contribution

摘要

Continuous monitoring of bowel activity during normal daily activities would improve clinical diagnostics and understanding the mechanisms underlying bowel function or help validate interventions that alter bowel function. This work describes a colon monitor to capture activity (ColoMOCA). The ColoMOCA included two pressure sensors, three impedance-sensing electrodes, and wireless battery recharge and data transmission circuitry. Components were integrated on a flexible printed circuit board, which was encapsulated in biocompatible silicone. Packaged ColoMOCAs were 8 mm in diameter and 85 mm long. ColoMOCAs continuously transmitted sensor data at 10Hz at 30 cm range, and ran for 21 hours before wireless recharge. Acute in vivo testing in conscious pigs demonstrated ColoMOCA detected colon phasic contractions with comparable accuracy relative to wired manometry sensors. Implantations of 7 days were performed which demonstrated conscious, ambulatory monitoring of colonic behavior, including phasic stool impedance data suggesting motility detection.

原文English
主出版物標題2022 IEEE Sensors, SENSORS 2022 - Conference Proceedings
發行者Institute of Electrical and Electronics Engineers Inc.
ISBN(電子)9781665484640
DOIs
出版狀態Published - 2022
事件2022 IEEE Sensors Conference, SENSORS 2022 - Dallas, United States
持續時間: 2022 10月 302022 11月 2

出版系列

名字Proceedings of IEEE Sensors
2022-October
ISSN(列印)1930-0395
ISSN(電子)2168-9229

Conference

Conference2022 IEEE Sensors Conference, SENSORS 2022
國家/地區United States
城市Dallas
期間22-10-3022-11-02

All Science Journal Classification (ASJC) codes

  • 電氣與電子工程

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