Musculoskeletal changes in children prenatally exposed to polychlorinated biphenyls and related compounds (yucheng children)

Y. L. Guo, C. J. Lin, W. J. Yao, J. J. Ryan, C. C. Hsu

研究成果: Article同行評審

55 引文 斯高帕斯(Scopus)

摘要

Fiftyfive YuCheng (oildisease) children born between 1978 and 1985 to mothers who ate PCBcontaminated rice oil in 1978-1979 were studied and compared to age and sex matched control subjects in 1991. The children’s growth profiles, bone mineral density and soft tissue composition, joint laxity, and serum parathyroid hormone, vitamin D, calcium, alkaline phosphatase, and phosphate were compared. The YuCheng children were 3.1 cm (p <.05) smaller and had less total lean mass and soft tissue mass as compared to the matched control subjects. All other parameters studied were similar in both groups. The shorter height and decreased total lean mass and soft tissue content were only seen in the YuCheng children who were the first born after the ingestion, but not in subsequent children. This was most likely due to decreased body burdens of the PCBs and related contaminants over time in the mothers.

原文English
頁(從 - 到)83-93
頁數11
期刊Journal of Toxicology and Environmental Health
41
發行號1
DOIs
出版狀態Published - 1994 一月 1

All Science Journal Classification (ASJC) codes

  • Toxicology
  • Pollution

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