Myelodysplastic syndrome with multilineage blast transformation: Special stains for optimal cytodiagnosis

Wu Chou Su, Chyurng Fung Jiann, Fang Show Liou, Tsai Woei

研究成果: Article

摘要

Transformation of myelodysplastic syndrome to hematologic malignancies is not uncommon, but involvement of three committed progenitor cell lines at one time is seldom seen. We present a case of myelodysplastic syndrome with blast transformation, neoplastic cells that were difficult to classify morphologically, and basophilia found in marrow and peripheral blood. Differential diagnosis included myeloblastic leukemia, erythroblastic leukemia, megakaryoblastic leukemia, basophiloblastic leukemia, and systemic mast cell disease (SMCD). By using a battery of cytochemical techniques and irnrnuno-tochemicalm ethods, we were able to demonstrate the presence of myeloblasts, erythroblasts, and megakaryoblasts, thus excluding the possibility of SMCD and basophiloblastic leukemia. (The J Histotechnol 13:67, 1990).

原文English
頁(從 - 到)67-70
頁數4
期刊Journal of Histotechnology
13
發行號1
DOIs
出版狀態Published - 1990 三月

All Science Journal Classification (ASJC) codes

  • Anatomy
  • Histology
  • Medical Laboratory Technology

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