Nanoshell magnetic resonance imaging contrast agents

Chia Hao Su, Hwo Shuenn Sheu, Chia Yun Lin, Chih Chia Huang, Yi Wei Lo, Ying Chih Pu, Jun Cheng Weng, Dar Bin Shieh, Jyh Horng Chen, Chen Sheng Yeh

研究成果: Conference contribution

摘要

In our studies, Au3Cu1 hollow nanostructures are believed to be the first bimetallic MR contrast agents. AU3CU 1 nanocapsules enhanced signal contrast not only in Ti-weighted imaging, but also in T2-weighted imaging at lower doses. Herein, we believe that the cooperativity originating from the form of the nanoparticles and the large surface area of the water, because of porous hollow morphology of the nanoparticle, are primarily involved. Furthermore, the amine groups on the outermost PEI polymer shell of the nanocapsules, which further provide surface modification for the attachment of biological signals, suggest great potential for use in multifunctional composite capsules as functional carriers and imaging agents. Overall, these results might lead to the creation of other non-Gd- and non-iron oxide-based bimetallic contrast agents.

原文English
主出版物標題Digest of Papers - Microprocesses and Nanotechnology 2007; 20th International Microprocesses and Nanotechnology Conference, MNC
頁面272-273
頁數2
DOIs
出版狀態Published - 2007
事件s20th International Microprocesses and Nanotechnology Conference, MNC 2007 - Kyoto, Japan
持續時間: 2007 11月 52007 11月 8

出版系列

名字Digest of Papers - Microprocesses and Nanotechnology 2007; 20th International Microprocesses and Nanotechnology Conference, MNC

Other

Others20th International Microprocesses and Nanotechnology Conference, MNC 2007
國家/地區Japan
城市Kyoto
期間07-11-0507-11-08

All Science Journal Classification (ASJC) codes

  • 硬體和架構
  • 電氣與電子工程

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