Naphthoquinone esters from the root of Rhinacanthus nasutus

Tian Shung Wu, Hua Chun Hsu, Pei Lin Wu, Yann Lii Leu, Yu Yi Chan, Ching Yuh Chern, Mou Yung Yeh, Hsien Ju Tien

研究成果: Article同行評審

50 引文 斯高帕斯(Scopus)

摘要

Reinvestigation of the root of Rhinacanthus nasutus afforded, in addition to rhinacanthin-A to -D reported previously, two new dimethyldihydropyranonaphthoquinone esters (5, 6) and eight new 2-hydroxy- 1,4-naphthoquinone esters (7-14) were isolated. The stereochemistry of rhinacanthin-A was determined as the R configuration. Compounds rhinacanthin- G to -N, belong to a class of 2-hydroxy-3-(3-hydroxy-2,2-dimethylpropyl)- 1,4-naphthoquinone esters, and so far have been isolated only in this plant. Their biosynthesis is also discussed.

原文English
頁(從 - 到)413-418
頁數6
期刊Chemical and Pharmaceutical Bulletin
46
發行號3
DOIs
出版狀態Published - 1998 一月 1

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Drug Discovery

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