Neonatal screening for alpha-thalassemia in southern Taiwan.

T. M. Lin, H. L. Eng, P. L. Kuo, H. L. Wu

研究成果: Article同行評審

6 引文 斯高帕斯(Scopus)

摘要

Screening peripheral or cord blood from newborn infants has been used for early detection of alpha-thalassemia conditions. The level of hemoglobin Bart's (Hb Bart's) in the blood correlates with the degree of alpha-gene deletion. Hence, the degree of gene deletion in an alpha-thalassemia carrier state can be estimated. Two thousand cord blood samples collected from the Tainan area were screened with cellulose acetate membrane electrophoresis for Hb Bart's. Ninety-nine of the 2,000 samples (4.95%) were positive for Hb Bart's. Concentrations of Hb Bart's varied from 3.2% to 30.7%. Of the 99 cases with Hb Bart's, 22 had Hb Bart's levels of 3.0% to 9.9%; 54 had Hb Bart's levels of 10.0% to 19.9%; and 23 had Hb Bart's levels of 20% to 40%. Routine cord blood screening by hemoglobin electrophoresis is recommended.

原文English
頁(從 - 到)1213-1215
頁數3
期刊Journal of the Formosan Medical Association = Taiwan yi zhi
91
發行號12
出版狀態Published - 1992 十二月

All Science Journal Classification (ASJC) codes

  • Medicine(all)

指紋 深入研究「Neonatal screening for alpha-thalassemia in southern Taiwan.」主題。共同形成了獨特的指紋。

引用此