Neurodevelopment of surviving infants at age two years, with a birthweight less than 2000 g and cared for in neonatal intensive care units (NICU) - Results from a population based longitudinal study in Taiwan

S. T. Wang, C. J. Wang, C. C. Huang, C. H. Lin

研究成果: Article

6 引文 (Scopus)

摘要

All surviving infants from nine neonatal intensive care units (NICU) in a southern city and county of Taiwan were followed up and assessed at 2 y of age if they had a birthweight of less than 2000 g and were born between February 1, 1993 and January 31, 1994. The assessments included: neurological, growth and general health. A comparison group of normal birthweight and full-term infants without congenital anomalies, matched by birth month and sex to the NICU survivors was also studied with respect to the same outcome measures. A developmental delay (either a severe neurological deficit or Mental Development Index < 68 or Psychomotor Development Index < 68) was present in 21 (15.4%) of the cases, compared to 3 (2.5%) of the controls (P < 0.0004). Significant correlates of developmental outcome for the cases were birthweight, gestational age, and maternal education. The very low birthweight (VLBW) children (< 1500 g) in our study cohort had a comparatively higher incidence of severe neurological deficits (and cerebral palsy) than that reported by other similar studies in developed countries. The incidence of abnormal neurodevelopmental outcome remained high in the graduates of NICU at 2 y of age, compared to that in normal controls. The findings have important implications in future health policy making regarding postnatal management of the surviving infants of NICU in developing countries such as Taiwan.

原文English
頁(從 - 到)331-336
頁數6
期刊Public Health
112
發行號5
DOIs
出版狀態Published - 1998 一月 1

指紋

Neonatal Intensive Care Units
Taiwan
Longitudinal Studies
Population
Surrogate Mothers
Policy Making
Incidence
Cerebral Palsy
Health Policy
Developed Countries
Developing Countries
Gestational Age
Survivors
Cohort Studies
Outcome Assessment (Health Care)
Parturition
Education
Health
Growth

All Science Journal Classification (ASJC) codes

  • Public Health, Environmental and Occupational Health

引用此文

@article{1f2d8dacfcba4b6da45a229e5bf47366,
title = "Neurodevelopment of surviving infants at age two years, with a birthweight less than 2000 g and cared for in neonatal intensive care units (NICU) - Results from a population based longitudinal study in Taiwan",
abstract = "All surviving infants from nine neonatal intensive care units (NICU) in a southern city and county of Taiwan were followed up and assessed at 2 y of age if they had a birthweight of less than 2000 g and were born between February 1, 1993 and January 31, 1994. The assessments included: neurological, growth and general health. A comparison group of normal birthweight and full-term infants without congenital anomalies, matched by birth month and sex to the NICU survivors was also studied with respect to the same outcome measures. A developmental delay (either a severe neurological deficit or Mental Development Index < 68 or Psychomotor Development Index < 68) was present in 21 (15.4{\%}) of the cases, compared to 3 (2.5{\%}) of the controls (P < 0.0004). Significant correlates of developmental outcome for the cases were birthweight, gestational age, and maternal education. The very low birthweight (VLBW) children (< 1500 g) in our study cohort had a comparatively higher incidence of severe neurological deficits (and cerebral palsy) than that reported by other similar studies in developed countries. The incidence of abnormal neurodevelopmental outcome remained high in the graduates of NICU at 2 y of age, compared to that in normal controls. The findings have important implications in future health policy making regarding postnatal management of the surviving infants of NICU in developing countries such as Taiwan.",
author = "Wang, {S. T.} and Wang, {C. J.} and Huang, {C. C.} and Lin, {C. H.}",
year = "1998",
month = "1",
day = "1",
doi = "10.1016/S0033-3506(98)00265-0",
language = "English",
volume = "112",
pages = "331--336",
journal = "Public Health",
issn = "0033-3506",
publisher = "Elsevier",
number = "5",

}

TY - JOUR

T1 - Neurodevelopment of surviving infants at age two years, with a birthweight less than 2000 g and cared for in neonatal intensive care units (NICU) - Results from a population based longitudinal study in Taiwan

AU - Wang, S. T.

AU - Wang, C. J.

AU - Huang, C. C.

AU - Lin, C. H.

PY - 1998/1/1

Y1 - 1998/1/1

N2 - All surviving infants from nine neonatal intensive care units (NICU) in a southern city and county of Taiwan were followed up and assessed at 2 y of age if they had a birthweight of less than 2000 g and were born between February 1, 1993 and January 31, 1994. The assessments included: neurological, growth and general health. A comparison group of normal birthweight and full-term infants without congenital anomalies, matched by birth month and sex to the NICU survivors was also studied with respect to the same outcome measures. A developmental delay (either a severe neurological deficit or Mental Development Index < 68 or Psychomotor Development Index < 68) was present in 21 (15.4%) of the cases, compared to 3 (2.5%) of the controls (P < 0.0004). Significant correlates of developmental outcome for the cases were birthweight, gestational age, and maternal education. The very low birthweight (VLBW) children (< 1500 g) in our study cohort had a comparatively higher incidence of severe neurological deficits (and cerebral palsy) than that reported by other similar studies in developed countries. The incidence of abnormal neurodevelopmental outcome remained high in the graduates of NICU at 2 y of age, compared to that in normal controls. The findings have important implications in future health policy making regarding postnatal management of the surviving infants of NICU in developing countries such as Taiwan.

AB - All surviving infants from nine neonatal intensive care units (NICU) in a southern city and county of Taiwan were followed up and assessed at 2 y of age if they had a birthweight of less than 2000 g and were born between February 1, 1993 and January 31, 1994. The assessments included: neurological, growth and general health. A comparison group of normal birthweight and full-term infants without congenital anomalies, matched by birth month and sex to the NICU survivors was also studied with respect to the same outcome measures. A developmental delay (either a severe neurological deficit or Mental Development Index < 68 or Psychomotor Development Index < 68) was present in 21 (15.4%) of the cases, compared to 3 (2.5%) of the controls (P < 0.0004). Significant correlates of developmental outcome for the cases were birthweight, gestational age, and maternal education. The very low birthweight (VLBW) children (< 1500 g) in our study cohort had a comparatively higher incidence of severe neurological deficits (and cerebral palsy) than that reported by other similar studies in developed countries. The incidence of abnormal neurodevelopmental outcome remained high in the graduates of NICU at 2 y of age, compared to that in normal controls. The findings have important implications in future health policy making regarding postnatal management of the surviving infants of NICU in developing countries such as Taiwan.

UR - http://www.scopus.com/inward/record.url?scp=0031759583&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031759583&partnerID=8YFLogxK

U2 - 10.1016/S0033-3506(98)00265-0

DO - 10.1016/S0033-3506(98)00265-0

M3 - Article

C2 - 9807931

AN - SCOPUS:0031759583

VL - 112

SP - 331

EP - 336

JO - Public Health

JF - Public Health

SN - 0033-3506

IS - 5

ER -