New diterpenoids and the bioactivity of Erythrophleum fordii

Chuan Chung Tsao, Yuh Chiang Shen, Chung Ren Su, Chia Ying Li, Meei Jen Liou, Nguyen Xuan Dung, Tian Shung Wu

研究成果: Article同行評審

27 引文 斯高帕斯(Scopus)

摘要

A phytochemical investigation of the leaves of Erythrophleum fordii Oliv. has led to the isolation of three new cassaine-type diterpenoids, erythrofordin A (1), erythrofordin B (2) and erythrofordin C (3), as well as a norcassaine diterpenoid with a novel skeleton, norerythrofordin A (4), and 27 known compounds (5-31). The structures of 1-4 were elucidated on the basis of spectroscopic analysis. Selected compounds from this plant were examined for anti-inflammatory activity. Taraxerol (16) displayed potent NO-reducing activity in microglial cells, and gallic acid (27) exhibited excellent DPPH radical-scavenging effects. Crown

原文English
頁(從 - 到)9867-9870
頁數4
期刊Bioorganic and Medicinal Chemistry
16
發行號22
DOIs
出版狀態Published - 2008 十一月 15

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

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