New insight into congestive heart failure and chronic obstructive pulmonary disease - A common but ignored concomittant disease

Hsiao Lun Tseng, Wen-Huang Li, Ting-Hsing Chao, Yang-Che Hsueh, Yao-Yi Huang, Yi-Heng Li, Liang-Miin Tsai

研究成果: Review article

摘要

The coexistence of congestive heart failure and chronic obstructive pulmonary disease is common in patients with acute dyspnea. The frequency of coexistence is far beyond our imagination. Clinical diagnosis is difficult to make because they share common but nonspecific symptoms and signs. Brain natriuretic peptide (BNP) is a useful serum biomarker to differentiate acute exacerbation of congestive heart failure from chronic obstructive pulmonary disease. Acute exacerbation of congestive heart failure could be excluded if BNP level is less than 100 pg/mL. Acute exacerbation of congestive heart failure is highly suspected if BPN level is more than 500 pg/mL. Treatment of this common concomitant disease is usually suboptimal because of being afraid of their contra-indication. To the best of our knowledge, there is no large clinical trial regarding this issue so far. In this review, we try to highlight the comorbidity, prognostic impact, diagnostic confusion and therapeutic dilemma of both diseases.

原文English
頁(從 - 到)1-8
頁數8
期刊Journal of Internal Medicine of Taiwan
22
發行號1
出版狀態Published - 2011 二月

指紋

Chronic Obstructive Pulmonary Disease
Heart Failure
Brain Natriuretic Peptide
Imagination
Confusion
Dyspnea
Signs and Symptoms
Comorbidity
Biomarkers
Clinical Trials
Therapeutics
Serum

All Science Journal Classification (ASJC) codes

  • Internal Medicine

引用此文

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abstract = "The coexistence of congestive heart failure and chronic obstructive pulmonary disease is common in patients with acute dyspnea. The frequency of coexistence is far beyond our imagination. Clinical diagnosis is difficult to make because they share common but nonspecific symptoms and signs. Brain natriuretic peptide (BNP) is a useful serum biomarker to differentiate acute exacerbation of congestive heart failure from chronic obstructive pulmonary disease. Acute exacerbation of congestive heart failure could be excluded if BNP level is less than 100 pg/mL. Acute exacerbation of congestive heart failure is highly suspected if BPN level is more than 500 pg/mL. Treatment of this common concomitant disease is usually suboptimal because of being afraid of their contra-indication. To the best of our knowledge, there is no large clinical trial regarding this issue so far. In this review, we try to highlight the comorbidity, prognostic impact, diagnostic confusion and therapeutic dilemma of both diseases.",
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