TY - JOUR
T1 - Nitrate transporters and peptide transporters
AU - Tsay, Yi Fang
AU - Chiu, Chi Chou
AU - Tsai, Chyn Bey
AU - Ho, Cheng Hsun
AU - Hsu, Po Kai
N1 - Funding Information:
We thank Ching-Shu Suen and Dr. Ming-Jing Hwang from Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan for phylogenetic analysis of NRT1 (PTR) family. We thank Dr. Gary Stacey for making available to us his unpublished results. Work in the Tsay lab is supported by grants from the National Science Council (NSC 95-2321-B-001-001) and Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan.
PY - 2007/5/25
Y1 - 2007/5/25
N2 - In higher plants, two types of nitrate transporters, NRT1 and NRT2, have been identified. In Arabidopsis, there are 53 NRT1 genes and 7 NRT2 genes. NRT2 are high-affinity nitrate transporters, while most members of the NRT1 family are low-affinity nitrate transporters. The exception is CHL1 (AtNRT1.1), which is a dual-affinity nitrate transporter, its mode of action being switched by phosphorylation and dephosphorylation of threonine 101. Two of the NRT1 genes, CHL1 and AtNRT1.2, and two of the NRT2 genes, AtNRT2.1 and AtNRT2.2, are known to be involved in nitrate uptake. In addition, AtNRT1.4 is required for petiole nitrate storage. On the other hand, some members of the NRT1 family are dipeptide transporters, called PTRs, which transport a broad spectrum of di/tripeptides. In barley, HvPTR1, expressed in the plasma membrane of scutellar epithelial cells, is involved in mobilizing peptides, produced by hydrolysis of endosperm storage protein, to the developing embryo. In higher plants, there is another family of peptide transporters, called oligopeptide transporters (OPTs), which transport tetra/pentapeptides. In addition, some OPTs transport GSH, GSSH, GSH conjugates, phytochelatins, and metals.
AB - In higher plants, two types of nitrate transporters, NRT1 and NRT2, have been identified. In Arabidopsis, there are 53 NRT1 genes and 7 NRT2 genes. NRT2 are high-affinity nitrate transporters, while most members of the NRT1 family are low-affinity nitrate transporters. The exception is CHL1 (AtNRT1.1), which is a dual-affinity nitrate transporter, its mode of action being switched by phosphorylation and dephosphorylation of threonine 101. Two of the NRT1 genes, CHL1 and AtNRT1.2, and two of the NRT2 genes, AtNRT2.1 and AtNRT2.2, are known to be involved in nitrate uptake. In addition, AtNRT1.4 is required for petiole nitrate storage. On the other hand, some members of the NRT1 family are dipeptide transporters, called PTRs, which transport a broad spectrum of di/tripeptides. In barley, HvPTR1, expressed in the plasma membrane of scutellar epithelial cells, is involved in mobilizing peptides, produced by hydrolysis of endosperm storage protein, to the developing embryo. In higher plants, there is another family of peptide transporters, called oligopeptide transporters (OPTs), which transport tetra/pentapeptides. In addition, some OPTs transport GSH, GSSH, GSH conjugates, phytochelatins, and metals.
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U2 - 10.1016/j.febslet.2007.04.047
DO - 10.1016/j.febslet.2007.04.047
M3 - Short survey
C2 - 17481610
AN - SCOPUS:34248193815
SN - 0014-5793
VL - 581
SP - 2290
EP - 2300
JO - FEBS Letters
JF - FEBS Letters
IS - 12
ER -