Noninvasive transcutaneous bilirubin assessment of neonates with hyperbilirubinemia using a photon diffusion theory-based method

Nan Yu Cheng, Yi Ling Lin, Ming Chien Fang, Wen Hsien Lu, Chin Chieh Yang, Sheng Hao Tseng

研究成果: Article

1 引文 斯高帕斯(Scopus)

摘要

Transcutaneous bilirubinometers are widely used to screen neonatal jaundice. However, it was reported that their accuracy is compromised at low and high bilirubin levels. We used a photon diffusion theory-based method valid in the 450–600 nm wavelength region to overcome this obstacle. Our clinical study results showed that our system could properly determine the transcutaneous bilirubin concentrations at total serum bilirubin levels higher than 14 mg/dL, where a commercial bilirubinometer failed to provide proper results in several cases. These findings suggested that photon diffusion theory could be employed to improve the core algorithm of modern bilirubinometers and enhance their applicability.

原文English
頁(從 - 到)2969-2984
頁數16
期刊Biomedical Optics Express
10
發行號6
DOIs
出版狀態Published - 2019 六月 1

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Atomic and Molecular Physics, and Optics

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