A novel monolithic off-shooter droplet generator has been demonstrated. The design, fabrication, bubble formation and droplet injection are described in this paper. It is different from the conventional droplet generators of top-shooter, side-shooter and back-shooter for injection. The droplet ejected from such off-shooter generator has the merits of straight trajectory with satellite improvement by two bubbles cutting and strong structure of stacked metal-polymer or polymer-polymer layers by integration of two-photoresist lithography and electroforming technologies. It is potentially used for inkjet printing, LCD color filter dispersion, microarray for bio application and so on.