On-chip cholangiocarcinoma cell capture and immunofluorescence staining for clinical diagnosis by using bile juice and whole blood

Lien Yu Hung, Wei Chun Tsai, Chien Yu Fu, Nai Jung Chiang, Yu Chun Wang, Yan-Shen Shan, Gwo Bin Lee

研究成果: Conference contribution

摘要

Cholangiocarcinoma (CCA) is the second most common primary liver cancer. There are several existing biomarkers targeting liver cancer. However, none of them are specific to CCA. It is therefore challenging to diagnose CCA in the early stages. In this study, a new integrated microfluidic system was developed for rapid, on-chip cell capture and immunofluorescence (IF) staining with CCA specific biomarkers for CCA clinical diagnosis. Rare CCA cells were successfully captured and stained from clinical bile juice and whole blood.

原文English
主出版物標題20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
發行者Chemical and Biological Microsystems Society
頁面563-564
頁數2
ISBN(電子)9780979806490
出版狀態Published - 2016 一月 1
事件20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 - Dublin, Ireland
持續時間: 2016 十月 92016 十月 13

出版系列

名字20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016

Other

Other20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
國家Ireland
城市Dublin
期間16-10-0916-10-13

指紋

Biomarkers
Liver
Blood
Microfluidics

All Science Journal Classification (ASJC) codes

  • Control and Systems Engineering

引用此文

Hung, L. Y., Tsai, W. C., Fu, C. Y., Chiang, N. J., Wang, Y. C., Shan, Y-S., & Lee, G. B. (2016). On-chip cholangiocarcinoma cell capture and immunofluorescence staining for clinical diagnosis by using bile juice and whole blood. 於 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 (頁 563-564). (20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016). Chemical and Biological Microsystems Society.
Hung, Lien Yu ; Tsai, Wei Chun ; Fu, Chien Yu ; Chiang, Nai Jung ; Wang, Yu Chun ; Shan, Yan-Shen ; Lee, Gwo Bin. / On-chip cholangiocarcinoma cell capture and immunofluorescence staining for clinical diagnosis by using bile juice and whole blood. 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016. Chemical and Biological Microsystems Society, 2016. 頁 563-564 (20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016).
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title = "On-chip cholangiocarcinoma cell capture and immunofluorescence staining for clinical diagnosis by using bile juice and whole blood",
abstract = "Cholangiocarcinoma (CCA) is the second most common primary liver cancer. There are several existing biomarkers targeting liver cancer. However, none of them are specific to CCA. It is therefore challenging to diagnose CCA in the early stages. In this study, a new integrated microfluidic system was developed for rapid, on-chip cell capture and immunofluorescence (IF) staining with CCA specific biomarkers for CCA clinical diagnosis. Rare CCA cells were successfully captured and stained from clinical bile juice and whole blood.",
author = "Hung, {Lien Yu} and Tsai, {Wei Chun} and Fu, {Chien Yu} and Chiang, {Nai Jung} and Wang, {Yu Chun} and Yan-Shen Shan and Lee, {Gwo Bin}",
year = "2016",
month = "1",
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language = "English",
series = "20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016",
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Hung, LY, Tsai, WC, Fu, CY, Chiang, NJ, Wang, YC, Shan, Y-S & Lee, GB 2016, On-chip cholangiocarcinoma cell capture and immunofluorescence staining for clinical diagnosis by using bile juice and whole blood. 於 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016. 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016, Chemical and Biological Microsystems Society, 頁 563-564, 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016, Dublin, Ireland, 16-10-09.

On-chip cholangiocarcinoma cell capture and immunofluorescence staining for clinical diagnosis by using bile juice and whole blood. / Hung, Lien Yu; Tsai, Wei Chun; Fu, Chien Yu; Chiang, Nai Jung; Wang, Yu Chun; Shan, Yan-Shen; Lee, Gwo Bin.

20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016. Chemical and Biological Microsystems Society, 2016. p. 563-564 (20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016).

研究成果: Conference contribution

TY - GEN

T1 - On-chip cholangiocarcinoma cell capture and immunofluorescence staining for clinical diagnosis by using bile juice and whole blood

AU - Hung, Lien Yu

AU - Tsai, Wei Chun

AU - Fu, Chien Yu

AU - Chiang, Nai Jung

AU - Wang, Yu Chun

AU - Shan, Yan-Shen

AU - Lee, Gwo Bin

PY - 2016/1/1

Y1 - 2016/1/1

N2 - Cholangiocarcinoma (CCA) is the second most common primary liver cancer. There are several existing biomarkers targeting liver cancer. However, none of them are specific to CCA. It is therefore challenging to diagnose CCA in the early stages. In this study, a new integrated microfluidic system was developed for rapid, on-chip cell capture and immunofluorescence (IF) staining with CCA specific biomarkers for CCA clinical diagnosis. Rare CCA cells were successfully captured and stained from clinical bile juice and whole blood.

AB - Cholangiocarcinoma (CCA) is the second most common primary liver cancer. There are several existing biomarkers targeting liver cancer. However, none of them are specific to CCA. It is therefore challenging to diagnose CCA in the early stages. In this study, a new integrated microfluidic system was developed for rapid, on-chip cell capture and immunofluorescence (IF) staining with CCA specific biomarkers for CCA clinical diagnosis. Rare CCA cells were successfully captured and stained from clinical bile juice and whole blood.

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M3 - Conference contribution

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T3 - 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016

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BT - 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016

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Hung LY, Tsai WC, Fu CY, Chiang NJ, Wang YC, Shan Y-S 等. On-chip cholangiocarcinoma cell capture and immunofluorescence staining for clinical diagnosis by using bile juice and whole blood. 於 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016. Chemical and Biological Microsystems Society. 2016. p. 563-564. (20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016).