Origins of replication: timing and chromosomal position

Joyce L. Hamlin, James P. Vaughn, Pieter A. Dijkwel, Tzeng Horng Leu, Chi Ma

研究成果: Article

5 引文 斯高帕斯(Scopus)


Several new methods have been used to localize replication initiation sites in mammalian chromosomes. The results of these studies argue strongly for the presence of defined sequence elements that function much like the origins in the genomes of simple microorganisms. However, relatively disparate results from in vivo and in vitro studies suggest that initiation reactions in mammalian chromosomes may have unique features, possibly related to a more complicated chromosomal architecture.

頁(從 - 到)414-421
期刊Current Opinion in Cell Biology
出版狀態Published - 1991 六月

All Science Journal Classification (ASJC) codes

  • Cell Biology

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