Patents and the development on polymer based nanomaterial (PAMAM dendrimer) for biomedical applications

Damaramadugu Rajasekhar, Pao Chi Liao

研究成果: Review article

2 引文 斯高帕斯(Scopus)

摘要

Dendrimers have found extensive convention in varied fields of biomedical engineering. Particularly, polyamidoamine (PAMAM) dendrimers have been found to have unique properties, and also interesting researches in the field of biomedical engineering have been recognized, when compared to other class of dendrimers. PAMAM dendrimers are biofriendly synthetic substances, and broadly studied dendrimers for biomedical applications, especially as therapeutic compositions. The focus of this review (citing 188 references) is on PAMAM dendrimer developments for biomedical applications, with prominence on conjugations for their extensive applications in the field of biomedical engineering and comparisons between classical (Tomalia PAMAM dendrimers) and novel (Baker-Huang PAMAM dendrimers) PAMAM dendrimers are also discussed by covering recent patents on PAMAM dendrimers. Finally, the use of PAMAM dendrimers in the field of proteomics, especially for use in phosphopeptide enrichment is presented. The future work points at the promises of developments.

原文English
頁(從 - 到)159-174
頁數16
期刊Recent Patents on Biomedical Engineering
5
發行號2
DOIs
出版狀態Published - 2012 一月 1

All Science Journal Classification (ASJC) codes

  • Bioengineering
  • Medicine (miscellaneous)
  • Biomedical Engineering

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