Pathological functions of hypoxia in endometriosis

研究成果: Article

2 引文 (Scopus)

摘要

Endometriosis is one of the most common gynecological diseases that significantly reduce the life quality of affected women. Research results from the past decade clearly demonstrated that aberrant production of estrogen and cyclooxygenase-2-derived prostaglandin E2 play indispensable roles in the pathogenesis of this disease. However, the etiology of endometriosis remains obscure. Recent evidence reveals a new facet of endometriotic pathogenesis by showing that hypoxia induces the expression of many important downstream genes to regulate the implantation, survival, and maintenance of ectopic endometriotic lesions. These new findings shed lights on future investigations of delineating the etiology of endometriosis and designing new therapeutic strategy for endometriosis.

原文English
頁(從 - 到)352-366
頁數15
期刊Frontiers in Bioscience - Elite
7E
發行號2
DOIs
出版狀態Published - 2015 一月 15

指紋

Endometriosis
Cyclooxygenase 2
Dinoprostone
Estrogens
Genes
Maintenance
Quality of Life
Light
Survival
Hypoxia
Research
Therapeutics

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)

引用此文

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Pathological functions of hypoxia in endometriosis. / Hsiao, Kuei Yang; Lin, Shih-Chieh; Wu, Meng-Hsing; Tsai, Shaw-Jenq.

於: Frontiers in Bioscience - Elite, 卷 7E, 編號 2, 15.01.2015, p. 352-366.

研究成果: Article

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