Pathological functions of hypoxia in endometriosis

研究成果: Review article同行評審

26 引文 斯高帕斯(Scopus)

摘要

Endometriosis is one of the most common gynecological diseases that significantly reduce the life quality of affected women. Research results from the past decade clearly demonstrated that aberrant production of estrogen and cyclooxygenase-2-derived prostaglandin E2 play indispensable roles in the pathogenesis of this disease. However, the etiology of endometriosis remains obscure. Recent evidence reveals a new facet of endometriotic pathogenesis by showing that hypoxia induces the expression of many important downstream genes to regulate the implantation, survival, and maintenance of ectopic endometriotic lesions. These new findings shed lights on future investigations of delineating the etiology of endometriosis and designing new therapeutic strategy for endometriosis.

原文English
頁(從 - 到)309-321
頁數13
期刊Frontiers in bioscience (Elite edition)
7
出版狀態Published - 2015

All Science Journal Classification (ASJC) codes

  • 生物化學、遺傳與分子生物學 (全部)
  • 免疫學與微生物學 (全部)

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