Peliosis hepatis in a kidney transplant recipient with manifestation as massive ascites and liver dysfunction: Case report

W. H. Lui, T. C. Chou, S. S. Chang, C. J. Hung, Y. J. Lin, P. C. Lee

研究成果: Article同行評審

8 引文 斯高帕斯(Scopus)

摘要

We report a case of 59-year-old woman who received a kidney transplant 7 years earlier without evidence of viral hepatitis history. She was asymptomatic initially and a newly developed nodule, ∼2.3 cm in size, was discovered in the right liver during routine sonographic examination. Computerized tomography-guided biopsy was inconclusive at that time. However, the lesion grew to 6.8 cm and bilobular multiple nodules developed with concomitant massive ascites and hyperbilirubinemia months later. Laparoscopy showed typical bluish-reddish-blackish nodules. Needle-biopsy histology showed severe sinusoid dilation and dropout of centrilobular hepatocytes consistent with peliosis hepatis. Reticulin staining also demonstrated disruption of sinusoidal reticulin fibers. We tried to withdraw possible offending drugs to anticipate regression of peliosis, but it failed and liver dysfunction progressed, leaving liver transplant as the last resort in such rare circumstances.

原文English
頁(從 - 到)630-633
頁數4
期刊Transplantation Proceedings
46
發行號2
DOIs
出版狀態Published - 2014 3月

All Science Journal Classification (ASJC) codes

  • 手術
  • 移植

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