Persistent hyperinsulinemic hypoglycemia of infancy: A case report

Shang Chun Tsai, Chau Jing Chen, Chyi Her Lin, Yuh Jyh Lin, Shio Jean Lin

研究成果: Article同行評審


Persistent hyperinsulinemic hypoglycemia of infancy (PHHI), though rare, is the most common cause of persistent hypoglycemia in early infancy. This disease is a clinically and genetically heterogeneous entity. Neonatal hyperinsulinemic hypoglycemia is often resistant to medical therapy and requires near-total pancreatectomy. We report on a baby girl who had hyperinsulinemic hypoglycemia from birth and finally improved after receiving a near-total pancreatectomy at the age of 71 days. Histology of the resected specimen showed characteristic diffuse hyperinsulinism. The likely cause in this type of PHHI was loss of KATPchannel (ATP sensitive potassium channel)function. At the age of one and half years old, there were no obvious sequelae, and her development was within normal limits.

頁(從 - 到)28-31
期刊Clinical Neonatology
出版狀態Published - 2002 12月

All Science Journal Classification (ASJC) codes

  • 兒科、圍產兒和兒童健康


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