Plasma free amino acid profile in cancer patients

Hong Shiee Lai, Jenq Chang Lee, Po Huang Lee, Shan Tair Wang, Wei Jao Chen

研究成果: Review article同行評審

135 引文 斯高帕斯(Scopus)

摘要

Redistribution or translocation of plasma free amino acids (PFAAs) to support visceral or tumor protein synthesis is an essential feature in cancer patients. An abnormal PFAA profile might be presented via the total reflection of cancer-induced protein metabolism in tumors, skeletal muscle and the liver in cancer patients. Clinical data from 13 studies have demonstrated a cancer-related PFAA profile, especially in digestive organ cancers. The PFAA profile can differ between the early and late stages of cancer. The profile is also affected by the type of cancer. Therefore, it is postulated that a detailed analysis of the PFAA profile may serve as one of the biological markers for cancer patients.

原文English
頁(從 - 到)267-276
頁數10
期刊Seminars in Cancer Biology
15
發行號4
DOIs
出版狀態Published - 2005 8月

All Science Journal Classification (ASJC) codes

  • 癌症研究

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