Point-of-care testing of portable blood coagulation detectors using optical sensors

Chin Lung Yang, Yan Chao Chiou, Cheng Wei Chou, Kung Chia Young, Song Jeng Huang, Chih Yi Liu

研究成果: Article同行評審

1 引文 斯高帕斯(Scopus)

摘要

A portable optical blood coagulation detector is proposed for point-of-care testing for determining prothrombin time (PT). The detector is applicable to sending the results to a computer via wireless transmission. The integrated apparatus comprises an optical module, a signal processing module, and a communication module for directly sensing real-time changes of transmittance during the blood coagulation process. The efficacy of the proposed device was validated with patients' whole blood specimens. Only a small amount of whole blood (approximately 60 μl) is required. The mean relative error of the PT values obtained using the proposed device is 4.8 ± 3.5% (less than one second) compared with the PT values obtained using the standard manual PT method (n = 26). The two testing platforms have highly correlated results (r = 0.997, p < 0.001). The proposed device has advantages of portability, ease of operation, real-time results, accuracy, carrying a potential for remote monitoring in the personalized long-distance healthcare industry.

原文English
頁(從 - 到)319-324
頁數6
期刊Journal of Medical and Biological Engineering
33
發行號3
DOIs
出版狀態Published - 2013

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering

指紋 深入研究「Point-of-care testing of portable blood coagulation detectors using optical sensors」主題。共同形成了獨特的指紋。

引用此