Postural stability of patients with schizophrenia during challenging sensory conditions: Implication of sensory integration for postural control

Ya Ling Teng, Chiung Ling Chen, Shu Zon Lou, Wei Tsan Wang, Jui Yen Wu, Hui Ing Ma, Vincent Chin Hung Chen

研究成果: Article同行評審

12 引文 斯高帕斯(Scopus)

摘要

Postural dysfunctions are prevalent in patients with schizophrenia and affect their daily life and ability to work. In addition, sensory functions and sensory integration that are crucial for postural control are also compromised. This study intended to examine how patients with schizophrenia coordinate multiple sensory systems to maintain postural stability in dynamic sensory conditions. Twenty-nine patients with schizophrenia and 32 control subjects were recruited. Postural stability of the participants was examined in six sensory conditions of different level of congruency of multiple sensory information, which was based on combinations of correct, removed, or conflicting sensory inputs from visual, somatosensory, and vestibular systems. The excursion of the center of pressure was measured by posturography. Equilibrium scores were derived to indicate the range of anterior-posterior (AP) postural sway, and sensory ratios were calculated to explore ability to use sensory information to maintain balance. The overall AP postural sway was significantly larger for patients with schizophrenia compared to the controls [patients (69.62±8.99); controls (76.53±7.47); t1,59 = -3.28, p<0.001]. The results of mixed-model ANOVAs showed a significant interaction between the group and sensory conditions [F5,295 = 5.55, p<0.001]. Further analysis indicated that AP postural sway was significantly larger for patients compared to the controls in conditions containing unreliable somatosensory information either with visual deprivation or with conflicting visual information. Sensory ratios were not significantly different between groups, although small and non-significant difference in inefficiency to utilize vestibular information was also noted. No significant correlations were found between postural stability and clinical characteristics. To sum up, patients with schizophrenia showed increased postural sway and a higher rate of falls during challenging sensory conditions, which was independent of clinical characteristics. Patients further demonstrated similar pattern and level of utilizing sensory information to maintain balance compared to the controls.

原文English
文章編號e0158219
期刊PloS one
11
發行號6
DOIs
出版狀態Published - 2016 6月

All Science Journal Classification (ASJC) codes

  • 多學科

指紋

深入研究「Postural stability of patients with schizophrenia during challenging sensory conditions: Implication of sensory integration for postural control」主題。共同形成了獨特的指紋。

引用此