TY - JOUR
T1 - Predicting Fetal Growth Restriction With Renal Volume Using 3-D Ultrasound
T2 - Efficacy Evaluation
AU - Chang, Chiung Hsin
AU - Tsai, Pei Yin
AU - Yu, Chen Hsiang
AU - Ko, Huei Chen
AU - Chang, Fong Ming
N1 - Funding Information:
This study was supported in part by grants to FMC and CHC from the National Science Council, Executive Yuan, Taipei, Taiwan. The authors are grateful to Ms. Chi-Ling Chen, Yueh-Chin Cheng and Yi-Jen Wang for their assistance.
PY - 2008/4
Y1 - 2008/4
N2 - Early detection and management of fetal growth restriction (FGR) is very important in prenatal care and daily practice, because FGR fetuses may suffer increased risk of perinatal morbidity and mortality. Renal volume (RV) might be one of the important parameters of fetal growth. Yet, no prenatal assessment of fetal RV in FGR fetuses by 3-D ultrasound (US) has been reported. We undertook a prospective and cross-sectional study using quantitative 3-D US to assess the efficacy of fetal RV in predicting FGR. All fetuses were singletons and were followed-up to delivery to determine whether they had FGR complications. In total, 221 fetuses without FGR and 28 fetuses with FGR were included. Our results showed fetal RV assessed by 3-D US can differentiate fetuses with FGR from fetuses without FGR. The best predicting threshold for FGR is at the tenth percentile of fetal RV. Using the tenth percentile as the cutoff, the efficacy of fetal RV in predicting FGR was sensitivity 96.4%, specificity 95.9%, positive predictive value 75.0%, negative predictive value 99.5% and accuracy 96.0%, respectively. Fetal RV assessed by 3-D US can be applied to detect FGR prenatally. We believe fetal RV assessment using 3-D US is a useful test in detecting fetuses with FGR. (E-mail: [email protected]).
AB - Early detection and management of fetal growth restriction (FGR) is very important in prenatal care and daily practice, because FGR fetuses may suffer increased risk of perinatal morbidity and mortality. Renal volume (RV) might be one of the important parameters of fetal growth. Yet, no prenatal assessment of fetal RV in FGR fetuses by 3-D ultrasound (US) has been reported. We undertook a prospective and cross-sectional study using quantitative 3-D US to assess the efficacy of fetal RV in predicting FGR. All fetuses were singletons and were followed-up to delivery to determine whether they had FGR complications. In total, 221 fetuses without FGR and 28 fetuses with FGR were included. Our results showed fetal RV assessed by 3-D US can differentiate fetuses with FGR from fetuses without FGR. The best predicting threshold for FGR is at the tenth percentile of fetal RV. Using the tenth percentile as the cutoff, the efficacy of fetal RV in predicting FGR was sensitivity 96.4%, specificity 95.9%, positive predictive value 75.0%, negative predictive value 99.5% and accuracy 96.0%, respectively. Fetal RV assessed by 3-D US can be applied to detect FGR prenatally. We believe fetal RV assessment using 3-D US is a useful test in detecting fetuses with FGR. (E-mail: [email protected]).
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U2 - 10.1016/j.ultrasmedbio.2007.10.006
DO - 10.1016/j.ultrasmedbio.2007.10.006
M3 - Article
C2 - 18055097
AN - SCOPUS:40949165278
SN - 0301-5629
VL - 34
SP - 533
EP - 537
JO - Ultrasound in Medicine and Biology
JF - Ultrasound in Medicine and Biology
IS - 4
ER -