TY - JOUR
T1 - Prenatal diagnosis of fetal omphalocele by ultrasound
T2 - A comparison of two centuries
AU - Liang, Yu Ling
AU - Kang, Lin
AU - Tsai, Pei Ying
AU - Cheng, Yueh Chin
AU - Ko, Huei Chen
AU - Chang, Chiung Hsin
AU - Chang, Fong Ming
N1 - Funding Information:
We are very grateful to the assistance of Dr Ta-Sheng Chen for editing the computer database. Our special thanks moreover go to the staff of Prenatal Ultrasound Lab, Department of Obstetrics and Gynecology, National Cheng Kung University Medical College and Hospital, This series was supported in part by a grant from the National Science Council, Executive Yuan, Taipei, Taiwan .
PY - 2013/6
Y1 - 2013/6
N2 - An omphalocele, a fetal abdominal defect, is a very important congenital anomaly. Prenatal diagnosis of fetal omphalocele is crucial to clinical management. Objective: To investigate the accuracy of prenatal diagnosis for fetal omphalocele, we undertook a retrospective and consecutive analysis of our ultrasound database between January 1994 and December 2011. Materials and Methods: In total, ultrasound (US) detected 52 fetuses with an omphalocele in utero. Results: The incidence of fetal omphalocele is estimated as 1:1249 (0.08%). We also compared the gestational age at US diagnosis between the two centuries. In the 20th century, 22 cases of omphalocele were detected: four (18%) cases at first trimester, 17 (77%) cases at second trimester, and 1 (5%) case at third trimester. In the 21st century, 30 cases of omphalocele were detected: 13 (43%) cases at first trimester, 15 (50%) cases at second trimester, and two (7%) cases at third trimester. The gestational age at diagnosis of omphalocele is significantly earlier in the 21st century than in the last century. Conclusion: With the advancement and improvement in US equipment, the early detection of fetal omphalocele is feasible, which will substantially contribute to fetal wellbeing.
AB - An omphalocele, a fetal abdominal defect, is a very important congenital anomaly. Prenatal diagnosis of fetal omphalocele is crucial to clinical management. Objective: To investigate the accuracy of prenatal diagnosis for fetal omphalocele, we undertook a retrospective and consecutive analysis of our ultrasound database between January 1994 and December 2011. Materials and Methods: In total, ultrasound (US) detected 52 fetuses with an omphalocele in utero. Results: The incidence of fetal omphalocele is estimated as 1:1249 (0.08%). We also compared the gestational age at US diagnosis between the two centuries. In the 20th century, 22 cases of omphalocele were detected: four (18%) cases at first trimester, 17 (77%) cases at second trimester, and 1 (5%) case at third trimester. In the 21st century, 30 cases of omphalocele were detected: 13 (43%) cases at first trimester, 15 (50%) cases at second trimester, and two (7%) cases at third trimester. The gestational age at diagnosis of omphalocele is significantly earlier in the 21st century than in the last century. Conclusion: With the advancement and improvement in US equipment, the early detection of fetal omphalocele is feasible, which will substantially contribute to fetal wellbeing.
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U2 - 10.1016/j.tjog.2013.04.018
DO - 10.1016/j.tjog.2013.04.018
M3 - Article
C2 - 23915861
AN - SCOPUS:84881022645
SN - 1028-4559
VL - 52
SP - 258
EP - 263
JO - Taiwanese Journal of Obstetrics and Gynecology
JF - Taiwanese Journal of Obstetrics and Gynecology
IS - 2
ER -