Prognostic role of tumor-head volume ratio in fetal sacrococcygeal teratoma

Edgar D. Sy, Roy A. Filly, Mei Leng Cheong, Matthew S. Clifton, Raul A. Cortes, Shinsuke Ohashi, Katsunari Takifuji, Denise Estefan Ventura, Erich J. Grethel, Amy J. Wagner, Elizabeth A. Gress, Robert H. Ball, Hanmin Lee, Michael R. Harrison

研究成果: Article同行評審

21 引文 斯高帕斯(Scopus)


Objective: To evaluate the ability of a tumor-head volume ratio to predict outcome and incidence of hydrops in fetuses with sacrococcygeal teratoma. Methods: Seventy-one sonograms were reviewed retrospectively from 28 fetuses with sacrococcygeal teratoma managed in our institution. Head volume (HV) and total tumor volume were calculated from sonograms. Amount of cystic tumor was estimated to determine solid tumor volume (STV) for the STV/HV ratio. Results: Twenty percent of sonograms with STV/HV <1 and 97.3% with STV/HV >1 were associated with 1 or more abnormal sonographic signs (p = 0.000). Overall mortality was 11/27 (41%). There was no mortality in fetuses with a ratio of <1, while 11/18 (61%) of fetuses with ratio >1 died (p = 0.003). Conclusion: The STV/HV ratio may be used to identify fetuses with a high risk of a poor outcome due to high-output cardiac failure and hydrops, and may help guide management.

頁(從 - 到)75-80
期刊Fetal Diagnosis and Therapy
出版狀態Published - 2009 十月

All Science Journal Classification (ASJC) codes

  • 兒科、圍產兒和兒童健康
  • 胚胎學
  • 放射學、核子醫學和影像學
  • 婦產科


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