Protein tyrosine phosphatase SHP2 suppresses podosome rosette formation in Src-transformed fibroblasts

Keyphrases

• Actin 12%
• Cell Motility 12%
• Dephosphorylation 12%
• Extracellular Matrix Degradation 12%
• High Content 12%
• Inhibitory Effect 12%
• Invasive Cancer Cell 12%
• Knockdown 12%
• Membrane Protrusion 12%
• Negative Regulator 12%
• Osteoclast 12%
• Overexpression 12%
• Phosphatase 100%
• Phosphatase Activity 12%
• Podosome 37%
• Podosome Rosettes 100%
• Polymerized 12%
• Protein Tyrosine Phosphatase 1B (PTP1B) 100%
• Rho Kinase 25%
• Rosette Formation 100%
• Rosette-like 12%
• Scaffold Protein 12%
• Self-assembly 12%
• Tks5 25%
• Transformed Fibroblasts 100%
• Tyrosine Kinase 12%
• Tyrosine Phosphorylation 12%
• Vimentin 12%
• Vimentin Intermediate Filaments 25%

Biochemistry, Genetics and Molecular Biology

• Actin 9%
• Cancer Cell 9%
• Cell Migration 9%
• Cell Motility 9%
• Dephosphorylation 9%
• Fibroblast 100%
• Kinase 18%
• Osteoclast 9%
• Phosphatase 100%
• Phosphotransferase 18%
• Podosome 100%
• Protein Tyrosine Phosphatase 100%
• Receptor Tyrosine Kinase 9%
• Rosette Formation 100%
• Scaffold Protein 9%
• Tyrosine Phosphorylation 9%
• Vimentin 27%

Immunology and Microbiology

• Actin 9%
• Cancer Cell 9%
• Cell Migration 9%
• Cell Motility 9%
• Dephosphorylation 9%
• Extracellular Matrix 9%
• Fibroblast 100%
• Osteoclast 9%
• Podosome 100%
• Protein Phosphorylation 9%
• Rosette Formation 100%
• Tyrosine 100%