Pulmonary elimination of 5‐fluorouracil in anesthetized rats

Yea‐Huei ‐H Kao, Chyun‐Yu ‐Y Yang, Russel R.L. Chen, Jin‐Ding ‐D Huang

研究成果: Article同行評審

5 引文 斯高帕斯(Scopus)

摘要

The pharmacokinetics of 5‐fluorouracil (5‐FU) was investigated in tumor‐free anesthetized rats. Blood samples in the carotid artery and in the right atrium were sampled by cannulation during the steady‐state infusion of 5‐FU. Serum and blood samples were assayed by HPLC. After comparing the steady‐state concentration of 5‐FU in the right carotid artery with that in the right atrium, it was concluded that there was no pulmonary elimination of 5‐FU in the anesthetized rat.

原文English
頁(從 - 到)1095-1096
頁數2
期刊Journal of Pharmaceutical Sciences
74
發行號10
DOIs
出版狀態Published - 1985 10月

All Science Journal Classification (ASJC) codes

  • 藥學科學

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