RADIOFREQUENCY-INDUCED SYNCHRONIZATION OF IN SITU HYPERTHERMIA AND CHEMOTHERAPY VIA MAGNETIC-NANOCONJUGATES

貢獻的翻譯標題: 促進抗癌藥效之磁性奈米粒子

Dar-Bin Shieh (Inventor)

研究成果: Patent

摘要

The present invention relates to a magnetic nanoparticle for tumor therapy, comprising: a magnetic core; a shell encapsulating a surface of the magnetic core, wherein the shell is made of a polymer with carboxylic groups; a poly-nucleotide chain connected to a surface of the shell; an anti-tumor drug connected to the poly-nucleotide chain, wherein the anti-tumor drug comprises at least one functional group, and each of the functional group is independently a pyrimidine group or a purine group; and an antibody connected to the shell, wherein the antibody identifies a target tumor. In addition, the present invention further provides a method for manufacturing the magnetic nanoparticles for tumor therapy and a pharmaceutical composition containing the magnetic nanoparticles. Accordingly, the magnetic nanoparticle for tumor therapy of the present invention can achieve effective treatment of tumor by synergistic effects between hyperthermia and targeted chemotherapy.
貢獻的翻譯標題促進抗癌藥效之磁性奈米粒子
原文English
專利號9351941
出版狀態Published - 2013 十二月 19

指紋 深入研究「促進抗癌藥效之磁性奈米粒子」主題。共同形成了獨特的指紋。

引用此