Rapid characterization and separation of isogenic mutants of H. pylori by dielectrophoresis

Chi Chang Lin, Sheng Kai Li, Bor Shyang Sheu, Hsien Chang Chang

研究成果: Article同行評審

摘要

A simple, fast, real-time, and nondestructive analysis of protein expression in biological samples, such as membranes, based on dielectrophoresis is described. On the basis of the distinct differences in the dielectrophoretic properties of individual cell types, the wild-type BabA-positive Helicobacter pylori isolates and its BabA-negative isogenic mutant can be identified and separated. The herein-presented approach of using microelectrodes should be an easy-to-use, cheap, and rapid alternative to separate and distinguish the presence or absence of important outer-membrane proteins.

原文English
頁(從 - 到)433-436
頁數4
期刊Biomedical Engineering - Applications, Basis and Communications
21
發行號6
DOIs
出版狀態Published - 2009 12月

All Science Journal Classification (ASJC) codes

  • 生物物理學
  • 生物工程
  • 生物醫學工程

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