Rapid fabrication of microfluidic paper-based analytical devices by microembossing

Yi-Je Juang, Po Sheng Chen, Yu Wang

研究成果: Article

4 引文 (Scopus)

摘要

In this study, fabrication of microfluidic paper based analytical devices (μPADs) by microembossing was proposed. Different from the embossing methods described in the literature, the filter paper was embossed such that a protruded structure was formed, which subsequently became the channel after heating the wax at the backside of the filter paper. It was found that, when using the Whatman No. 3 filter paper, the embossing pressure needed to be larger than 50 kg/cm2 in conjunction with using a minimal 2-mm wide channel, and the wax heating time ranged from 15 to 45 s in order to obtain a reliable μPAD with repetitive and consistent results. In addition, there was no need of a hydrophobic material as the backside support. The glucose detection was demonstrated using the μPADs as fabricated and a linear relationship was obtained between 5 and 50 mM glucose concentrations. With the proposed method, the processing time of fabricating μPADs can be reduced within approximately 1 min.

原文English
頁(從 - 到)87-92
頁數6
期刊Sensors and Actuators, B: Chemical
283
DOIs
出版狀態Published - 2019 三月 15

指紋

Waxes
Microfluidics
Glucose
Heating
Fabrication
embossing
fabrication
waxes
filters
glucose
heating
Processing

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Instrumentation
  • Condensed Matter Physics
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Electrical and Electronic Engineering
  • Materials Chemistry

引用此文

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abstract = "In this study, fabrication of microfluidic paper based analytical devices (μPADs) by microembossing was proposed. Different from the embossing methods described in the literature, the filter paper was embossed such that a protruded structure was formed, which subsequently became the channel after heating the wax at the backside of the filter paper. It was found that, when using the Whatman No. 3 filter paper, the embossing pressure needed to be larger than 50 kg/cm2 in conjunction with using a minimal 2-mm wide channel, and the wax heating time ranged from 15 to 45 s in order to obtain a reliable μPAD with repetitive and consistent results. In addition, there was no need of a hydrophobic material as the backside support. The glucose detection was demonstrated using the μPADs as fabricated and a linear relationship was obtained between 5 and 50 mM glucose concentrations. With the proposed method, the processing time of fabricating μPADs can be reduced within approximately 1 min.",
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Rapid fabrication of microfluidic paper-based analytical devices by microembossing. / Juang, Yi-Je; Chen, Po Sheng; Wang, Yu.

於: Sensors and Actuators, B: Chemical, 卷 283, 15.03.2019, p. 87-92.

研究成果: Article

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AU - Wang, Yu

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