Rapidly in situ forming hydrophobically-modified chitosan hydrogels via pH-responsive nanostructure transformation

Ya Ling Chiu; Mei-Chin Chen; Chun Yu Chen; Po Wei Lee; Fwu Long Mi; U. Ser Jeng; Hsin Lung Chen; Hsing Wen Sung

doi:10.1039/b818906d

Rapidly in situ forming hydrophobically-modified chitosan hydrogels via pH-responsive nanostructure transformation

Ya Ling Chiu, Mei-Chin Chen, Chun Yu Chen, Po Wei Lee, Fwu Long Mi, U. Ser Jeng, Hsin Lung Chen, Hsing Wen Sung

化學工程學系

研究成果: Article › 同行評審

33 引文斯高帕斯（Scopus）

摘要

A pH-responsive hydrogel targeted for various biomedical applications has been developed using a naturally-abundant biopolymer, chitosan, with controlled grafting of hydrophobic side chains. The rapid hydrogelation is driven by a transformation of the nanostructure of the side-chain aggregates from local micelles to interconnected nanodomains in a sponge phase due to the dominance of hydrophobic interaction near physiological pH.

原文	English
頁（從 - 到）	962-965
頁數	4
期刊	Soft Matter
卷	5
發行號	5
DOIs	https://doi.org/10.1039/b818906d
出版狀態	Published - 2009 3月 5

All Science Journal Classification (ASJC) codes

化學 (全部)
凝聚態物理學

存取文件

10.1039/b818906d

其它文件與鏈接

引用此

@article{56e886bdf50d42f8a4302673e37f3299,

title = "Rapidly in situ forming hydrophobically-modified chitosan hydrogels via pH-responsive nanostructure transformation",

abstract = "A pH-responsive hydrogel targeted for various biomedical applications has been developed using a naturally-abundant biopolymer, chitosan, with controlled grafting of hydrophobic side chains. The rapid hydrogelation is driven by a transformation of the nanostructure of the side-chain aggregates from local micelles to interconnected nanodomains in a sponge phase due to the dominance of hydrophobic interaction near physiological pH.",

author = "Chiu, {Ya Ling} and Mei-Chin Chen and Chen, {Chun Yu} and Lee, {Po Wei} and Mi, {Fwu Long} and Jeng, {U. Ser} and Chen, {Hsin Lung} and Sung, {Hsing Wen}",

year = "2009",

month = mar,

day = "5",

doi = "10.1039/b818906d",

language = "English",

volume = "5",

pages = "962--965",

journal = "Soft Matter",

issn = "1744-683X",

publisher = "Royal Society of Chemistry",

number = "5",

}

TY - JOUR

T1 - Rapidly in situ forming hydrophobically-modified chitosan hydrogels via pH-responsive nanostructure transformation

AU - Chiu, Ya Ling

AU - Chen, Mei-Chin

AU - Chen, Chun Yu

AU - Lee, Po Wei

AU - Mi, Fwu Long

AU - Jeng, U. Ser

AU - Chen, Hsin Lung

AU - Sung, Hsing Wen

PY - 2009/3/5

Y1 - 2009/3/5

N2 - A pH-responsive hydrogel targeted for various biomedical applications has been developed using a naturally-abundant biopolymer, chitosan, with controlled grafting of hydrophobic side chains. The rapid hydrogelation is driven by a transformation of the nanostructure of the side-chain aggregates from local micelles to interconnected nanodomains in a sponge phase due to the dominance of hydrophobic interaction near physiological pH.

AB - A pH-responsive hydrogel targeted for various biomedical applications has been developed using a naturally-abundant biopolymer, chitosan, with controlled grafting of hydrophobic side chains. The rapid hydrogelation is driven by a transformation of the nanostructure of the side-chain aggregates from local micelles to interconnected nanodomains in a sponge phase due to the dominance of hydrophobic interaction near physiological pH.

UR - http://www.scopus.com/inward/record.url?scp=61349139996&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=61349139996&partnerID=8YFLogxK

U2 - 10.1039/b818906d

DO - 10.1039/b818906d

M3 - Article

AN - SCOPUS:61349139996

SN - 1744-683X

VL - 5

SP - 962

EP - 965

JO - Soft Matter

JF - Soft Matter

IS - 5

ER -

Rapidly in situ forming hydrophobically-modified chitosan hydrogels via pH-responsive nanostructure transformation

摘要

All Science Journal Classification (ASJC) codes

存取文件

其它文件與鏈接

指紋

引用此