Recalcitrant extragenital giant condyloma acuminatum: A need for combination therapy

研究成果: Article

摘要

Giant condyloma acuminatum (GCA), also known as Buschke -Löwenstein tumor, is a huge, rapidly growing variant of condyloma found in the anogenital region. Extragenital GCA is rare and, in most cases, affecting the intertriginous area and treated by excision. We described a case of refractory extragenital GCA involving the large part of the left axilla area successfully treated with immunotherapy and podophyllotoxin. Considering the large size and the location, the lesions were not treated by wide excision because it might result in scar contracture with limitation of shoulder movement or axillary web syndrome. Our case illustrates that combination therapy of podophyllotoxin, imiquimod plus weekly cryotherapy may be an effective and less invasive option for treating GCA of the axilla with good cosmetic and functional outcomes.

原文English
文章編號e12867
期刊Dermatologic Therapy
32
發行號3
DOIs
出版狀態Published - 2019 五月 1

指紋

Buschke-Lowenstein Tumor
Podophyllotoxin
Axilla
imiquimod
Cryotherapy
Contracture
Therapeutics
Cosmetics
Immunotherapy
Cicatrix
Neoplasms

All Science Journal Classification (ASJC) codes

  • Dermatology

引用此文

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abstract = "Giant condyloma acuminatum (GCA), also known as Buschke -L{\"o}wenstein tumor, is a huge, rapidly growing variant of condyloma found in the anogenital region. Extragenital GCA is rare and, in most cases, affecting the intertriginous area and treated by excision. We described a case of refractory extragenital GCA involving the large part of the left axilla area successfully treated with immunotherapy and podophyllotoxin. Considering the large size and the location, the lesions were not treated by wide excision because it might result in scar contracture with limitation of shoulder movement or axillary web syndrome. Our case illustrates that combination therapy of podophyllotoxin, imiquimod plus weekly cryotherapy may be an effective and less invasive option for treating GCA of the axilla with good cosmetic and functional outcomes.",
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