TY - JOUR
T1 - Recalcitrant extragenital giant condyloma acuminatum
T2 - A need for combination therapy
AU - Lee, Chaw Ning
AU - Hsu, Chao Kai
AU - Lee, Julia Yu Yun
N1 - Publisher Copyright:
© 2019 Wiley Periodicals, Inc.
PY - 2019/5/1
Y1 - 2019/5/1
N2 - Giant condyloma acuminatum (GCA), also known as Buschke -Löwenstein tumor, is a huge, rapidly growing variant of condyloma found in the anogenital region. Extragenital GCA is rare and, in most cases, affecting the intertriginous area and treated by excision. We described a case of refractory extragenital GCA involving the large part of the left axilla area successfully treated with immunotherapy and podophyllotoxin. Considering the large size and the location, the lesions were not treated by wide excision because it might result in scar contracture with limitation of shoulder movement or axillary web syndrome. Our case illustrates that combination therapy of podophyllotoxin, imiquimod plus weekly cryotherapy may be an effective and less invasive option for treating GCA of the axilla with good cosmetic and functional outcomes.
AB - Giant condyloma acuminatum (GCA), also known as Buschke -Löwenstein tumor, is a huge, rapidly growing variant of condyloma found in the anogenital region. Extragenital GCA is rare and, in most cases, affecting the intertriginous area and treated by excision. We described a case of refractory extragenital GCA involving the large part of the left axilla area successfully treated with immunotherapy and podophyllotoxin. Considering the large size and the location, the lesions were not treated by wide excision because it might result in scar contracture with limitation of shoulder movement or axillary web syndrome. Our case illustrates that combination therapy of podophyllotoxin, imiquimod plus weekly cryotherapy may be an effective and less invasive option for treating GCA of the axilla with good cosmetic and functional outcomes.
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U2 - 10.1111/dth.12867
DO - 10.1111/dth.12867
M3 - Article
C2 - 30834614
AN - SCOPUS:85067405788
SN - 1396-0296
VL - 32
JO - Dermatologic Therapy
JF - Dermatologic Therapy
IS - 3
M1 - e12867
ER -