Micromixers are crucial components within micro biomedical systems. This article presents a comprehensive review of the main state-of-the art applications of micromixers in biomedical systems over the past ten years. The article commences by reviewing the fundamental fluidic behaviors involved in microfluidic mixing. The biomedical applications of micromixers are then described in regard to their use particularly for (1) sample concentration, (2) chemical synthesis, (3) chemical reaction, (4) polymerization, (5) extraction and purification, (6) biological analysis, and (7) droplet/emulsion processes and others. The review concludes with a brief statistical analysis of the published literature in the micromixer field and an overview of the relative advantages of passive micromixers compared to active micromixers.
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