Repetitive sequence elements in an initiation locus of the amplified dihydrofolate reductase domain in CHO cells

Tzeng Horng Leu, Boyka Anachkova, Joyce L. Hamlin

研究成果: Article

16 引文 斯高帕斯(Scopus)

摘要

We have previously demonstrated that one of the replication initiation loci in the dihydrofolate reductase (DHFR) domain of Chinese hamster cells contains a repeated sequence that is enriched in the early-replicating fraction of the Chinese hamster genome. Here we present the sequence of the initiation locus, identify the relevant repeated element, and show that, while this element is enriched in early-replicating DNA, its synthesis is not confined to early S.

原文English
頁(從 - 到)428-433
頁數6
期刊Genomics
7
發行號3
DOIs
出版狀態Published - 1990 七月

All Science Journal Classification (ASJC) codes

  • Genetics

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