Review: Application of nanoparticles in urothelial cancer of the urinary bladder

Chieh Hsiao Chen, Tzu Min Chan, Yi Jhen Wu, Jia Jin Chen

研究成果: Review article同行評審

11 引文 斯高帕斯(Scopus)

摘要

Bladder cancer is a common malignancy of the urinary tract, which generally develops in the epithelial lining of the urinary bladder. The specific course of treatment depends on the stage of bladder cancer; however, therapeutic strategies typically involve intravesical drug delivery to reduce toxicity and increase therapeutic effects. Recently, metallic, polymeric, lipid, and protein nanoparticles have been introduced to aid in the treatment of bladder cancer. Nanoparticles are also commonly used as pharmaceutical carriers to improve interactions between drugs and the urothelium. In this review, we classify the characteristics of bladder cancer and discuss the types of nanoparticles used in various treatment modalities. Finallywe summarize the potential applications and benefits of various nanoparticles in intravesical therapy.

原文English
頁(從 - 到)419-427
頁數9
期刊Journal of Medical and Biological Engineering
35
發行號4
DOIs
出版狀態Published - 2015 八月

All Science Journal Classification (ASJC) codes

  • 生物醫學工程

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