Robust and brilliant Raman tags based on core-satellite assemblies for brain tumor cell imaging

Yung Ching Chang, Li Ching Huang, Wei Lun Sun, Shih Yi Chuang, Tien Hsin Lin, Yi Syuan Wu, Chun-I Sze, Shiuan-Yeh Chen

研究成果: Conference contribution

摘要

GBM (Glioblastoma Multiforme), a fatal brain tumor, is highly infiltrative and difficult to be completely removed by the surgery. In this work, the Raman tags based on the plasmonic core-satellite assemblies with ∼1 nm internal gap accompanied by extremely high gap field have been fabricated and applied to GBM cell labeling. The brightness of the Raman tags is comparable to the fluorophores. The GBM cells with overexpression of EGFR are labeled with these Raman tags and can be distinguished from the normal cells through Raman imaging.

原文English
主出版物標題Biomedical Vibrational Spectroscopy 2018
主出版物子標題Advances in Research and Industry
編輯Anita Mahadevan-Jansen, Wolfgang Petrich
發行者SPIE
ISBN(電子)9781510614659
DOIs
出版狀態Published - 2018 一月 1
事件Biomedical Vibrational Spectroscopy 2018: Advances in Research and Industry - San Francisco, United States
持續時間: 2018 一月 272018 一月 28

出版系列

名字Progress in Biomedical Optics and Imaging - Proceedings of SPIE
10490
ISSN(列印)1605-7422

Other

OtherBiomedical Vibrational Spectroscopy 2018: Advances in Research and Industry
國家United States
城市San Francisco
期間18-01-2718-01-28

指紋

Fluorophores
Glioblastoma
Brain Neoplasms
Surgery
Labeling
assemblies
brain
Tumors
Luminance
Brain
tumors
Cells
Satellites
Imaging techniques
cells
surgery
marking
brightness

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

引用此文

Chang, Y. C., Huang, L. C., Sun, W. L., Chuang, S. Y., Lin, T. H., Wu, Y. S., ... Chen, S-Y. (2018). Robust and brilliant Raman tags based on core-satellite assemblies for brain tumor cell imaging. 於 A. Mahadevan-Jansen, & W. Petrich (編輯), Biomedical Vibrational Spectroscopy 2018: Advances in Research and Industry [1049006] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; 卷 10490). SPIE. https://doi.org/10.1117/12.2290194
Chang, Yung Ching ; Huang, Li Ching ; Sun, Wei Lun ; Chuang, Shih Yi ; Lin, Tien Hsin ; Wu, Yi Syuan ; Sze, Chun-I ; Chen, Shiuan-Yeh. / Robust and brilliant Raman tags based on core-satellite assemblies for brain tumor cell imaging. Biomedical Vibrational Spectroscopy 2018: Advances in Research and Industry. 編輯 / Anita Mahadevan-Jansen ; Wolfgang Petrich. SPIE, 2018. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE).
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author = "Chang, {Yung Ching} and Huang, {Li Ching} and Sun, {Wei Lun} and Chuang, {Shih Yi} and Lin, {Tien Hsin} and Wu, {Yi Syuan} and Chun-I Sze and Shiuan-Yeh Chen",
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Chang, YC, Huang, LC, Sun, WL, Chuang, SY, Lin, TH, Wu, YS, Sze, C-I & Chen, S-Y 2018, Robust and brilliant Raman tags based on core-satellite assemblies for brain tumor cell imaging. 於 A Mahadevan-Jansen & W Petrich (編輯), Biomedical Vibrational Spectroscopy 2018: Advances in Research and Industry., 1049006, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, 卷 10490, SPIE, Biomedical Vibrational Spectroscopy 2018: Advances in Research and Industry, San Francisco, United States, 18-01-27. https://doi.org/10.1117/12.2290194

Robust and brilliant Raman tags based on core-satellite assemblies for brain tumor cell imaging. / Chang, Yung Ching; Huang, Li Ching; Sun, Wei Lun; Chuang, Shih Yi; Lin, Tien Hsin; Wu, Yi Syuan; Sze, Chun-I; Chen, Shiuan-Yeh.

Biomedical Vibrational Spectroscopy 2018: Advances in Research and Industry. 編輯 / Anita Mahadevan-Jansen; Wolfgang Petrich. SPIE, 2018. 1049006 (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; 卷 10490).

研究成果: Conference contribution

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AU - Chang, Yung Ching

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AU - Sze, Chun-I

AU - Chen, Shiuan-Yeh

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AB - GBM (Glioblastoma Multiforme), a fatal brain tumor, is highly infiltrative and difficult to be completely removed by the surgery. In this work, the Raman tags based on the plasmonic core-satellite assemblies with ∼1 nm internal gap accompanied by extremely high gap field have been fabricated and applied to GBM cell labeling. The brightness of the Raman tags is comparable to the fluorophores. The GBM cells with overexpression of EGFR are labeled with these Raman tags and can be distinguished from the normal cells through Raman imaging.

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Chang YC, Huang LC, Sun WL, Chuang SY, Lin TH, Wu YS 等. Robust and brilliant Raman tags based on core-satellite assemblies for brain tumor cell imaging. 於 Mahadevan-Jansen A, Petrich W, 編輯, Biomedical Vibrational Spectroscopy 2018: Advances in Research and Industry. SPIE. 2018. 1049006. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE). https://doi.org/10.1117/12.2290194