摘要
Endometriosis is one of the most common gynecological diseases, affecting approximately 10 % of women in reproductive age. It is characterized as the presence of endometrial-like glands and stroma outside the uterus, commonly on the pelvic peritoneum and ovaries. The major symptoms of endometriosis include pelvic pain, dysmenorrhea, dyspareunia, and infertility. During the past decade, intensive investigations on molecular mechanisms responsible for the pathological processes of endometriosis have been conducted. Although many factors have been reported to be involved in these processes, prostaglandin E2 (PGE2) no doubt represents as one of the most critical regulators of all. Accumulating data demonstrate that PGE2 controls many critical functions, such as steroidogenesis, angiogenesis, proliferation, and immune suppression that contribute to the pathogenesis of endometriosis. Herein, we will summarize the most up-to-date information regarding the functional roles of PGE2 in the development and maintenance of endometriosis.
| 原文 | English |
|---|---|
| 主出版物標題 | Endometriosis |
| 主出版物子標題 | Pathogenesis and Treatment |
| 發行者 | Springer Japan |
| 頁面 | 125-146 |
| 頁數 | 22 |
| 卷 | 9784431544210 |
| ISBN（電子） | 9784431544210 |
| ISBN（列印） | 4431544208, 9784431544203 |
| DOIs | |
| 出版狀態 | Published - 2014 一月 1 |
指紋
All Science Journal Classification (ASJC) codes
- Medicine(all)
引用此文
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Roles of prostaglandin E2 in endometriosis. / Hsiao, Kuei Yang; Wu, Meng-Hsing; Tsai, Shaw-Jenq.
Endometriosis: Pathogenesis and Treatment. 卷 9784431544210 Springer Japan, 2014. p. 125-146.研究成果: Chapter
TY - CHAP
T1 - Roles of prostaglandin E2 in endometriosis
AU - Hsiao, Kuei Yang
AU - Wu, Meng-Hsing
AU - Tsai, Shaw-Jenq
PY - 2014/1/1
Y1 - 2014/1/1
N2 - Endometriosis is one of the most common gynecological diseases, affecting approximately 10 % of women in reproductive age. It is characterized as the presence of endometrial-like glands and stroma outside the uterus, commonly on the pelvic peritoneum and ovaries. The major symptoms of endometriosis include pelvic pain, dysmenorrhea, dyspareunia, and infertility. During the past decade, intensive investigations on molecular mechanisms responsible for the pathological processes of endometriosis have been conducted. Although many factors have been reported to be involved in these processes, prostaglandin E2 (PGE2) no doubt represents as one of the most critical regulators of all. Accumulating data demonstrate that PGE2 controls many critical functions, such as steroidogenesis, angiogenesis, proliferation, and immune suppression that contribute to the pathogenesis of endometriosis. Herein, we will summarize the most up-to-date information regarding the functional roles of PGE2 in the development and maintenance of endometriosis.
AB - Endometriosis is one of the most common gynecological diseases, affecting approximately 10 % of women in reproductive age. It is characterized as the presence of endometrial-like glands and stroma outside the uterus, commonly on the pelvic peritoneum and ovaries. The major symptoms of endometriosis include pelvic pain, dysmenorrhea, dyspareunia, and infertility. During the past decade, intensive investigations on molecular mechanisms responsible for the pathological processes of endometriosis have been conducted. Although many factors have been reported to be involved in these processes, prostaglandin E2 (PGE2) no doubt represents as one of the most critical regulators of all. Accumulating data demonstrate that PGE2 controls many critical functions, such as steroidogenesis, angiogenesis, proliferation, and immune suppression that contribute to the pathogenesis of endometriosis. Herein, we will summarize the most up-to-date information regarding the functional roles of PGE2 in the development and maintenance of endometriosis.
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UR - http://www.scopus.com/inward/citedby.url?scp=84930724354&partnerID=8YFLogxK
U2 - 10.1007/978-4-431-54421-0_9
DO - 10.1007/978-4-431-54421-0_9
M3 - Chapter
AN - SCOPUS:84930724354
SN - 4431544208
SN - 9784431544203
VL - 9784431544210
SP - 125
EP - 146
BT - Endometriosis
PB - Springer Japan
ER -