Severe gangrene of the stomach and infarction of the liver and spleen after percutaneous ethanol injection for hepatocellular carcinoma: Report of a case

Kuo Chih Tseng, Shao Jer Chen, An Liang Chou, Jeh En Tzeng, Hong-Ming Tsai, Pin-Nan Cheng

研究成果: Article

1 引文 (Scopus)

摘要

Percutaneous ethanol injection is a safe and effective treatment for small hepatocellular carcinoma. The complication rate is lower in the injury of liver, stomach and spleen. We herein report an 82-year-old female with chronic hepatitis C-related hepatocellular carcinoma, measuring 4.0 × 2.8 cm in the left lobe of liver. Because of high risk of surgery, she received percutaneous ethanol injection in segmental fractions with 1-2 cc in one fraction, total 20 milliliter of 95% ethanol in one session, and then soon suffered complications of gangrene of the stomach and infarction of the liver and spleen. Although surgical intervention and intensive care were administrated, she finally died of sepsis with multiple organ failure. The mechanism of percutaneous ethanol injection-related injuries to a combination of stomach, liver and spleen is probably vascular injury by ethanol. It is recommended that a slower injection speed, small amounts of ethanol during procedure and assessment of vascular anatomy before percutaneous ethanol injection are needed to avoid such severe ethanol-induced vessel injury.

原文English
頁(從 - 到)33-38
頁數6
期刊Journal of Internal Medicine of Taiwan
17
發行號1
出版狀態Published - 2006 二月 1

指紋

Gangrene
Infarction
Hepatocellular Carcinoma
Stomach
Ethanol
Spleen
Injections
Liver
Wounds and Injuries
Multiple Organ Failure
Vascular System Injuries
Chronic Hepatitis C
Critical Care
Blood Vessels
Anatomy
Sepsis

All Science Journal Classification (ASJC) codes

  • Internal Medicine

引用此文

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abstract = "Percutaneous ethanol injection is a safe and effective treatment for small hepatocellular carcinoma. The complication rate is lower in the injury of liver, stomach and spleen. We herein report an 82-year-old female with chronic hepatitis C-related hepatocellular carcinoma, measuring 4.0 × 2.8 cm in the left lobe of liver. Because of high risk of surgery, she received percutaneous ethanol injection in segmental fractions with 1-2 cc in one fraction, total 20 milliliter of 95{\%} ethanol in one session, and then soon suffered complications of gangrene of the stomach and infarction of the liver and spleen. Although surgical intervention and intensive care were administrated, she finally died of sepsis with multiple organ failure. The mechanism of percutaneous ethanol injection-related injuries to a combination of stomach, liver and spleen is probably vascular injury by ethanol. It is recommended that a slower injection speed, small amounts of ethanol during procedure and assessment of vascular anatomy before percutaneous ethanol injection are needed to avoid such severe ethanol-induced vessel injury.",
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T1 - Severe gangrene of the stomach and infarction of the liver and spleen after percutaneous ethanol injection for hepatocellular carcinoma

T2 - Report of a case

AU - Tseng, Kuo Chih

AU - Chen, Shao Jer

AU - Chou, An Liang

AU - Tzeng, Jeh En

AU - Tsai, Hong-Ming

AU - Cheng, Pin-Nan

PY - 2006/2/1

Y1 - 2006/2/1

N2 - Percutaneous ethanol injection is a safe and effective treatment for small hepatocellular carcinoma. The complication rate is lower in the injury of liver, stomach and spleen. We herein report an 82-year-old female with chronic hepatitis C-related hepatocellular carcinoma, measuring 4.0 × 2.8 cm in the left lobe of liver. Because of high risk of surgery, she received percutaneous ethanol injection in segmental fractions with 1-2 cc in one fraction, total 20 milliliter of 95% ethanol in one session, and then soon suffered complications of gangrene of the stomach and infarction of the liver and spleen. Although surgical intervention and intensive care were administrated, she finally died of sepsis with multiple organ failure. The mechanism of percutaneous ethanol injection-related injuries to a combination of stomach, liver and spleen is probably vascular injury by ethanol. It is recommended that a slower injection speed, small amounts of ethanol during procedure and assessment of vascular anatomy before percutaneous ethanol injection are needed to avoid such severe ethanol-induced vessel injury.

AB - Percutaneous ethanol injection is a safe and effective treatment for small hepatocellular carcinoma. The complication rate is lower in the injury of liver, stomach and spleen. We herein report an 82-year-old female with chronic hepatitis C-related hepatocellular carcinoma, measuring 4.0 × 2.8 cm in the left lobe of liver. Because of high risk of surgery, she received percutaneous ethanol injection in segmental fractions with 1-2 cc in one fraction, total 20 milliliter of 95% ethanol in one session, and then soon suffered complications of gangrene of the stomach and infarction of the liver and spleen. Although surgical intervention and intensive care were administrated, she finally died of sepsis with multiple organ failure. The mechanism of percutaneous ethanol injection-related injuries to a combination of stomach, liver and spleen is probably vascular injury by ethanol. It is recommended that a slower injection speed, small amounts of ethanol during procedure and assessment of vascular anatomy before percutaneous ethanol injection are needed to avoid such severe ethanol-induced vessel injury.

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