Single cell detection using 3D magnetic rolled-up structures

Tzong Rong Ger, Hao Ting Huang, Chen Yu Huang, Mei Feng Lai

研究成果: Article

16 引文 斯高帕斯(Scopus)

摘要

A 3D rolled-up structure made of a SiO2 layer and a fishbone-like magnetic thin film was proposed here as a biosensor. The magnetoresistance (MR) measurement results of the sensor suggest that the presence of the stray field, which is induced by the magnetic nanoparticles, significantly increased the switching field. Comparing the performance of the 2D sensor and 3D sensor designed in this study, the response in switching field variation was 12.14% in the 2D sensor and 62.55% in the 3D sensor. The response in MR ratio variation was 4.55% in the 2D sensor and 82.32% in the 3D sensor. In addition, the design of the 3D sensor structure also helped to attract and trap a single magnetic cell due to its stronger stray field compared with the 2D structure. The 3D magnetic biosensor designed here can provide important information for future biochip research and applications.

原文English
頁(從 - 到)4225-4230
頁數6
期刊Lab on a Chip
13
發行號21
DOIs
出版狀態Published - 2013 十一月 7

All Science Journal Classification (ASJC) codes

  • Bioengineering
  • Biochemistry
  • Chemistry(all)
  • Biomedical Engineering

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