Single cell impedance analysis and electrical characterization in micro-fluidic device

Chia Feng Liu, Jen Yu Jao, Ming Kun Chen, Ya Chun Chuang, Pin Chian Wu, Ling Sheng Jang

研究成果: Conference contribution

4 引文 斯高帕斯(Scopus)

摘要

We introduces a study of single cell in a microfluidic device constructed from polydimethylsiloxane (PDMS) using micro-electro-mechanical-system (MEMS) technology, used to measure the characterization of single cells under liquid medium. The microfluidic device combines a microfluidic structure to capture single cell level and a coplanar waveguide electrode inside a channel to measure the impedance of a single HeLa cell (human cervical epithelioid carcinoma). The electrical characterization of a single cell is demonstrated using a two-port vector network analyzer (VNA) in the frequency range of 1 MHz - 1 GHz. The validity of the electrical equivalent model in this study is asserted through measurements of cell impedance in phosphate buffer solution (PBS) liquid, as well as electrical simulations of a single HeLa cell experiment compared with measurements.

原文English
主出版物標題NEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems
頁面121-126
頁數6
DOIs
出版狀態Published - 2011 十月 4
事件6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2011 - Kaohsiung, Taiwan
持續時間: 2011 二月 202011 二月 23

出版系列

名字NEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems

Other

Other6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2011
國家Taiwan
城市Kaohsiung
期間11-02-2011-02-23

All Science Journal Classification (ASJC) codes

  • Atomic and Molecular Physics, and Optics

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  • 引用此

    Liu, C. F., Jao, J. Y., Chen, M. K., Chuang, Y. C., Wu, P. C., & Jang, L. S. (2011). Single cell impedance analysis and electrical characterization in micro-fluidic device. 於 NEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (頁 121-126). [6017310] (NEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems). https://doi.org/10.1109/NEMS.2011.6017310