Sodium p-toluenesulfinate/copper(II) acetate in free radical reactions of 5-aryl substituted alkenes

Sheow Fong Wang, Che Ping Chuang, Jia Han Lee, Shui Te Liu

研究成果: Article同行評審

39 引文 斯高帕斯(Scopus)

摘要

p-Toluenesulfonyl radical can be generated from sodium p- toluenesulfinate in aqueous acetic acid or formic acid. Sulfonyl radical mediating reaction of 5-aryl substituted alkenes with sodium p- toluenesulfinate/copper(II) acetate gave p-toluenesulfonylmethyl substituted naphthalene and isoquinoline derivatives. This reaction proceeded much faster in aqueous formic acid than in aqueous acetic acid. The cyclization mode (Ar2-6 vs Ar1-5) of the 5-phenyl-1-butyl radical is strongly dependent on the geometry of the tether of the radical intermediate.

原文English
頁(從 - 到)2273-2288
頁數16
期刊Tetrahedron
55
發行號8
DOIs
出版狀態Published - 1999 2月 19

All Science Journal Classification (ASJC) codes

  • 生物化學
  • 藥物發現
  • 有機化學

指紋

深入研究「Sodium p-toluenesulfinate/copper(II) acetate in free radical reactions of 5-aryl substituted alkenes」主題。共同形成了獨特的指紋。

引用此