Spatial transcriptomics in human skin research

Stavroula Tekkela, Georgios Theocharidis, John A. McGrath, Alexandros Onoufriadis

研究成果: Review article同行評審

1 引文 斯高帕斯(Scopus)

摘要

Spatial transcriptomics is a revolutionary technique that enables researchers to characterise tissue architecture and localisation of gene expression. A plethora of technologies that map gene expression are currently being developed, aiming to facilitate spatially resolved, high-dimensional assessment of gene transcription in the context of human skin research. Knowing which gene is expressed by which cell and in which location within skin, facilitates understanding of skin function and dysfunction in both health and disease. In this review, we summarise the available spatial transcriptomic methods and we describe their application to a broad spectrum of dermatological diseases.

原文English
期刊Experimental Dermatology
DOIs
出版狀態Accepted/In press - 2023

All Science Journal Classification (ASJC) codes

  • 生物化學
  • 分子生物學
  • 皮膚科

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