Striatal dopamine D2/D3 receptor availability in male smokers

Yen Kuang Yang; Wei Jen Yao; Joseph P. McEvoy; Ching Lin Chu; I. Hui Lee; Po See Chen; Tzung Lieh Yeh; Nan Tsing Chiu

doi:10.1016/j.pscychresns.2005.09.008

Striatal dopamine D₂/D₃ receptor availability in male smokers

Yen Kuang Yang, Wei Jen Yao, Joseph P. McEvoy, Ching Lin Chu, I. Hui Lee, Po See Chen, Tzung Lieh Yeh, Nan Tsing Chiu

研究成果: Article › 同行評審

21 引文斯高帕斯（Scopus）

摘要

It has been reported that the activation of the nicotine receptor evokes central endogenous dopamine release. However, whether smoking affects striatal dopamine D₂/D₃ availability over the long run has not been well established in vivo. Fifteen male smokers and their matching controls were recruited. Striatal dopamine D₂/D₃ receptor availability was assessed by single photon emission computed tomography with [ ¹²³]IBZM Iodo-benzaimide. There was no significant difference in striatal D₂/D₃ receptor availability between smokers and controls.

原文	English
頁（從 - 到）	87-90
頁數	4
期刊	Psychiatry Research - Neuroimaging
卷	146
發行號	1
DOIs	https://doi.org/10.1016/j.pscychresns.2005.09.008
出版狀態	Published - 2006 1月 30

All Science Journal Classification (ASJC) codes

神經科學（雜項）
放射學、核子醫學和影像學
精神病學和心理健康

UN SDG

此研究成果有助於以下永續發展目標

存取文件

10.1016/j.pscychresns.2005.09.008

其它文件與鏈接

引用此

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abstract = "It has been reported that the activation of the nicotine receptor evokes central endogenous dopamine release. However, whether smoking affects striatal dopamine D2/D3 availability over the long run has not been well established in vivo. Fifteen male smokers and their matching controls were recruited. Striatal dopamine D2/D3 receptor availability was assessed by single photon emission computed tomography with [ 123]IBZM Iodo-benzaimide. There was no significant difference in striatal D2/D3 receptor availability between smokers and controls.",

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note = "Funding Information: The work was supported by a grant from the National Science Council of Taiwan (NSC 91-2314-B-006-074). The authors thank Mitchell Chen, Shu Chuan Lin, and Linda J. Chang for their assistance in the preparation of the article.",

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AU - Chen, Po See

AU - Yeh, Tzung Lieh

AU - Chiu, Nan Tsing

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