Structure and formation of microplasmin.

H. L. Wu, G. Y. Shi, R. C. Wohl, M. L. Bender

研究成果: Article同行評審

48 引文 斯高帕斯(Scopus)


The structure of human microplasmin, prepared from plasmin in alkaline solution, has been studied. Microplasmin consists of two polypeptide chains connected by disulfide bonds. One polypeptide is the B chain of plasmin consisting of 230 amino acids, and the other peptide is the COOH-terminal portion of the A chain of plasmin consisting of 31 amino acid residues. Microplasmin has a molecular weight of 28,635, calculated from its primary sequence. It is slightly more positively charged than plasminogen and is a more hydrophobic molecule. The proposed scheme for the formation of microplasmin involves autolysis at specific peptide bonds and scrambling of especially sensitive disulfide bonds in alkaline solution.

頁(從 - 到)8793-8795
期刊Proceedings of the National Academy of Sciences of the United States of America
出版狀態Published - 1987 十二月

All Science Journal Classification (ASJC) codes

  • 多學科


深入研究「Structure and formation of microplasmin.」主題。共同形成了獨特的指紋。