Structure and synthesis of clausenaquinone-a. A novel carbazolequinone alkaloid and bioactive principle from clausena excavata

Tian Shung Wu, Shiow Chyn Huang, Pei0Lin Wu, Kuo Hsiung Lee

研究成果: Article同行評審

25 引文 斯高帕斯(Scopus)

摘要

A new carbazolequinone alkaloid, clausenaquinone-A, has been isolated from the stem bark of Clausena excavata. The structure has been established from spectral data and total synthesis. Clausenaquinone-A shows potent inhibitory activity of the rabbit platelet aggregation as well as cytotoxicity in HCT-8, RPMI-7951, and TE671 tumor cells.

原文English
頁(從 - 到)2395-2398
頁數4
期刊Bioorganic and Medicinal Chemistry Letters
4
發行號20
DOIs
出版狀態Published - 1994

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

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