Studies of the sulfonated hydrogenated styrene–isoprene–styrene block copolymer and its surface properties, cytotoxicity, and platelet-contacting characteristics

Bin Hong Tsai, Tse An Lin, Chi Hui Cheng, Jui Che Lin

研究成果: Article同行評審

摘要

Styrenic thermoplastic elastomers (TPEs) consist of styrenic blocks. They are connected with other soft segments by a covalent linkage and are widely used in human life. However, in biomedical applications, TPEs need to be chemically hydrogenated in advance to enhance their properties such as strong UV/ozone resistance and thermal-oxidative stability. In this study, films composed of sulfonated hydrogenated TPEs were evaluated. Hydrogenated tert-butyl styrene–styrene–isoprene block copolymers were synthesized and selectively sulfonated to different degrees by reaction with acetyl sulfate. By controlling the ratio of the hydrogenated tert-butyl styrene–styrene–isoprene block copolymer and acetyl sulfate, sulfonated films were optimized to demonstrate sufficient mechanical integrity in water as well as good biocompatibility. The thermal plastic sulfonated films were found to be free of cytotoxicity and platelet-compatible and could be potential candidates in biomedical film applications such as wound dressings.

原文English
文章編號235
頁(從 - 到)1-13
頁數13
期刊Polymers
13
發行號2
DOIs
出版狀態Published - 2021 一月

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Polymers and Plastics

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