Study on the cell mechanics of MDCK cells by elastic micro-pillars arrays

Chien Wen Wang, Wei Ren Chen, Ching Chou Wu, Hsien Chang Chang

研究成果: Conference contribution

1 引文 斯高帕斯(Scopus)

摘要

The cellular force is one of the most important parameters of cellular physiological behavior and mechanical interactions between the cell and its environment which could regulate the cell migration, contractility and gene expression. In order to evidence the characteristics of the physiology and cellular mechanics of the epithelial cells, therefore, we use the micro-pillars arrays (MPAs) to measure the traction force of the Madin-Darby canine kidney (MDCK) cells. When MDCK cells adhere on the different geometry of MPAs, the cell will pull MPAs and cause the pillars displacement due to the traction force. Furthermore, the cellular image and the displacement of the pillars could be analyzed by optic microscope system, and could be evaluated the mechanical interactions between the cells and MPAs. Therefore, this method might help us understand the cellular mechanics and physiological phenomenon between the cells and underlying substrates.

原文English
主出版物標題Proceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007
頁面1125-1128
頁數4
DOIs
出版狀態Published - 2007 8月 28
事件2007 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007 - Bangkok, Thailand
持續時間: 2007 1月 162007 1月 19

出版系列

名字Proceedings of the 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007

Other

Other2007 2nd IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE NEMS 2007
國家/地區Thailand
城市Bangkok
期間07-01-1607-01-19

All Science Journal Classification (ASJC) codes

  • 電腦網路與通信
  • 電腦科學應用
  • 電氣與電子工程

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