Successful initial treatment with weekly 24-hour infusion of 5-fluorouracil and leucoyorin in a rectal cancer patient with acute disseminated intravascular coagulation

Wen Tsung Huang, Kung Chao Chang, Yan Shen Shan, Chao Jung Tsao, Jenq Chang Lee

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8 引文 斯高帕斯(Scopus)

摘要

Cancer-associated acute disseminated intravascular coagulation is rare in colorectal cancer, but is rapidly fatal when present. We present a case of a 79-year-old male who developed acute disseminated intravascular coagulation one month after receiving Hartmann's procedure for his rectal cancer. Peripheral blood showed leucoerythroblastosis while marrow carcinomatosis was noted by bone marrow examination. Prompt chemotherapy with weekly 24-h infusion of 5-fluorouracil and leucovorin were administered and the acute disseminated intravascular coagulation gradually resolved after 2 cycles of treatment. A total of 10 cycles of weekly chemotherapy were administered. The patient died of pneumonia on the 83rd day after diagnosis of disseminated intravascular coagulation without evidence of acute disseminated intravascular coagulation and tumor progression. We suggest that if acute disseminated intravascular coagulation developed after surgery for rectal cancer, the cancer-related acute disseminated intravascular coagulation should be taken into consideration. The immediate administration of chemotherapy may save the patient in time.

原文English
頁(從 - 到)1436-1439
頁數4
期刊Hepato-Gastroenterology
52
發行號65
出版狀態Published - 2005

All Science Journal Classification (ASJC) codes

  • 肝病
  • 消化內科

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